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[ 英語タイトル ] Next-Generation Sequencing (NGS) Market by Product (Hiseq, Miseq, Hiseq X Ten/X Five, NextSeq500, Ion Proton, PGM, Ions5, PacBio RSII), Services (Targeted, RNA, Exome, De Novo), & Application (Diagnostics, Biomarker, Agriculture) - Global Forecasts to 2022


Product Code : MNMHC00108110
Survey : MarketsandMarkets
Publish On : February, 2021
Category : Healthcare and Pharmaceuticals
Study Area : Global
Report format : PDF
Sales price option (consumption tax not included)
Single User USD5650 / Question Form
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[Report Description]

The global next-generation sequencing market is estimated to register a CAGR of 20.5% from 2017 to 2022 to reach USD 12.45 billion by 2022. Factors such as technological advancements in NGS platforms, increasing applications of NGS, growing partnerships and collaborations, and increasing adoption of NGS among research laboratories and academic institutes are driving the growth of this market. On the other hand, accuracy and standardization concerns in diagnostic testing and the lack of skilled technical personnel are some of the key factors limiting the growth of the market.

On the basis of product and service, the NGS market is categorized into pre-sequencing products and services, NGS platforms, consumables, services for platforms, sequencing services, and bioinformatics. In 2017, the consumables segment is expected to account for the largest share of the market.

On the basis of technology, the global NGS market is segmented into sequencing by synthesis (SBS), ion semiconductor sequencing, single-molecule real-time (SMRT) sequencing, and nanopore sequencing. In 2017, the SBS technology is expected to account for the largest share of the market, majorly due to the development of new and advanced NGS platforms, the increasing demand for Illumina’s systems (including the HiSeq series and MiSeq), and the growing demand for NextSeq and HiSeq X Ten.

Based on applications, the market is categorized into six segments, namely, diagnostics, drug discovery, biomarker discovery, precision medicine, agriculture & animal research, and other application. The diagnostics application segment is expected to account for the major share of the global NGS market owing to the increasing focus of key market players on providing & developing NGS-based diagnostic tests and the growing adoption of NGS-based diagnostic tests related to oncology and infectious diseases.

On the basis of end user, the market is segmented into research centers and academic & government institutes, hospitals & clinics, pharmaceutical & biotechnology companies, and other end users. Among these end users, the hospitals and clinics segment is expected to register the highest CAGR due to the growing number of agreements between companies and hospitals for the development of advanced tests and products catering to the specific needs of hospitals and clinics. For instance, in November 2016, Illumina, Inc. entered into an agreement with Mayo Clinic (U.S.) to install its BaseSpace Clarity LIMS in Mayo’s specific laboratories.

Geographically, the NGS market is segmented into North America, Europe, Asia-Pacific, and the Rest of the World. North America is expected to command the largest share of the market in 2017, followed by Europe. The market in North America is primarily driven by the technological advancements, availability of commercial solutions for NGS data analysis, and the strong presence of key players in this region. However, Asia-Pacific is expected to register the highest growth rate during the forecast period from 2017 to 2022, due to the improving healthcare infrastructure and favorable government initiatives in this region.
The global NGS market is highly competitive, with a large number of global and local players. In 2016, the global NGS market was dominated by Illumina, Inc. (U.S.), Thermo Fisher Scientific Inc. (U.S.), and Pacific Biosciences of California, Inc. (U.S.), and together held the majority share of the NGS platforms market. New product launches, product enhancements, agreements, and partnerships were the major strategies adopted by market players to achieve growth in the market.

Research Coverage
This report studies the next-generation sequencing (NGS) market based on product & service, application, technology, and end user. The report also studies factors (such as drivers, restraints, opportunities, and challenges) affecting market growth. It analyzes opportunities and challenges in the market for stakeholders and provides details of the competitive landscape for market leaders. Furthermore, the report analyzes micromarkets with respect to their individual growth trends, prospects, and contributions to the total market. The report forecasts the revenue of the market segments with respect to four main regions.

Reasons to Buy the Report:
From an insights perspective, this research report has focused on various levels of analysis—industry trends, market share analysis of top ten players, and company profiles, which together comprise and discuss basic views on the competitive landscape, emerging and high-growth segments of the next-generation sequencing market, and high-growth regions and countries and their respective drivers, restraints, challenges, and opportunities.

The report will enrich both established firms as well as new entrants/smaller firms to gauge the pulse of the market, which in turn will help firms garner greater market shares. Firms purchasing the report could use any one or a combination of the below-mentioned five strategies for strengthening their market shares.

The report provides insights on the following pointers:

• Market Penetration: Comprehensive information on product portfolios and services offered by the major players in the next-generation sequencing market. The report analyzes the next generation sequencing market based on product & service, application, technology, end user, and region

• Product Development/Innovation: Detailed insights on the upcoming technologies, research and development activities, and product launches in the next-generation sequencing market

• Market Development: Comprehensive information about lucrative emerging markets. The report analyzes the markets for various next-generation sequencing products and services across geographies

• Market Diversification: Exhaustive information about new products and services, untapped geographies, recent developments, and investments in the next-generation sequencing market

• Competitive Assessment: In-depth assessment of market shares, strategies, products and services, distribution networks, and manufacturing capabilities of leading players in the next-generation sequencing market

TABLE OF CONTENTS

1 INTRODUCTION 17
1.1 OBJECTIVES OF THE STUDY 17
1.2 MARKET DEFINITION 17
1.3 MARKET SCOPE 18
1.3.1 MARKETS COVERED 18
1.3.2 YEARS CONSIDERED FOR THE STUDY 20
1.4 CURRENCY 20
1.5 LIMITATIONS 20
1.6 STAKEHOLDERS 21
2 RESEARCH METHODOLOGY 22
2.1 RESEARCH METHODOLOGY STEPS 22
2.2 RESEARCH DESIGN 23
2.3 SECONDARY AND PRIMARY RESEARCH METHODOLOGY 24
2.3.1 SECONDARY RESEARCH 24
2.3.1.1 Key data from secondary sources 24
2.3.2 PRIMARY DATA 25
2.3.2.1 Breakdown of primaries 25
2.3.2.2 Key data from primary sources 26
2.3.2.3 Key industry insights 27
2.4 MARKET SIZE ESTIMATION 27
2.4.1.1 Bottom-up approach 28
2.4.1.2 Top-down approach 29
2.5 MARKET BREAKDOWN AND DATA TRIANGULATION 30
2.6 ASSUMPTIONS FOR THE STUDY 31
3 EXECUTIVE SUMMARY 32
3.1 INTRODUCTION 32
4 PREMIUM INSIGHTS 36
4.1 NEXT-GENERATION SEQUENCING (NGS): MARKET OVERVIEW 36
4.2 NGS MARKET, BY PRODUCT & SERVICE (2017 VS. 2022) 37
4.3 NGS MARKET SIZE, BY APPLICATION, 2017 VS. 2022 38
4.4 NGS MARKET, BY END USER (2017 VS. 2022) 38
4.5 GEOGRAPHIC ANALYSIS: NGS MARKET SIZE, BY PRODUCT & SERVICE (2017 VS. 2022), USD MILLION 39

5 MARKET OVERVIEW 40
5.1 INTRODUCTION 41
5.2 MARKET DYNAMICS 41
5.2.1 DRIVERS 42
5.2.1.1 Technological advancements in sequencing platforms 42
5.2.1.2 Increasing applications of NGS 42
5.2.1.3 Growing number of partnerships and collaborations 43
5.2.1.4 Increasing adoption of NGS technologies among research laboratories and academic institutes 44
5.2.1.5 Conferences and workshops increasing awareness on NGS products and services 44
5.2.2 RESTRAINTS 45
5.2.2.1 Dearth of skilled professionals 45
5.2.2.2 Difficulties in storage of sequencing data 45
5.2.3 OPPORTUNITIES 46
5.2.3.1 Government initiatives in population sequencing 46
5.2.3.2 Application of NGS in precision medicine & biomarker discovery 46
5.2.3.3 Emerging markets offer significant growth opportunities 47
5.2.3.4 Cloud computing, a prospective service 48
5.2.4 CHALLENGES 49
5.2.4.1 Interpretation of complex data from NGS platforms 49
5.2.4.2 Accuracy & standardization concerns in diagnostic testing 49
5.2.4.3 Issues related to the security of NGS data 49
5.2.5 INDUSTRY TRENDS 50
5.2.5.1 Integration of next-generation sequencing with cloud-based technology 50
5.2.5.2 Focus on cancer research 50
5.2.5.3 Mergers and acquisitions 51
5.2.5.4 Entry of new market players 52
6 NEXT-GENERATION SEQUENCING MARKET, BY PRODUCT & SERVICE 53
6.1 INTRODUCTION 54
6.2 PRE-SEQUENCING PRODUCTS & SERVICES MARKET 54
6.2.1 SAMPLE PREPARATION 55
6.2.1.1 DNA Fragmentation, End Repair, A-tailing, and Size Selection 56
6.2.1.2 Library Preparation & Target Enrichment 56
6.2.1.3 Quality Control 58
6.3 NGS PLATFORMS, CONSUMABLES, & SERVICES FOR PLATFORMS 59
6.3.1 NGS PLATFORMS MARKET 61
6.3.1.1 Illumina 61
6.3.1.1.1 HiSeq Series 62
6.3.1.1.2 HiSeq X Ten & HiSeq X Five 63
6.3.1.1.3 MiSeq Series 64
6.3.1.1.4 NextSeq 500 64
6.3.1.1.5 MiniSeq 65
6.3.1.2 Thermo Fisher Scientific (Life Technologies) 66
6.3.1.2.1 Ion PGM 66
6.3.1.2.2 Ion Proton 67
6.3.1.2.3 Ion S5 & S5 XL 68
6.3.1.3 Pacific Biosciences 68
6.3.1.3.1 PacBio RS II 69
6.3.1.3.2 Sequel System 70
6.3.1.4 Oxford Nanopore 70
6.3.1.5 Other Next-generation Sequencing Platforms 71
6.3.1.6 Recently Launched Sequencing Platforms 73
6.4 SEQUENCING SERVICES MARKET 74
6.4.1 TARGETED RE-SEQUENCING 75
6.4.2 RNA-SEQ 76
6.4.3 DE NOVO SEQUENCING 76
6.4.4 EXOME SEQUENCING 77
6.4.5 CHIP-SEQ 77
6.4.6 WHOLE-GENOME SEQUENCING 78
6.4.7 METHYL-SEQ 78
6.4.8 OTHER APPLICATIONS 78
6.5 NGS DATA ANALYSIS, STORAGE, AND MANAGEMENT (BIOINFORMATICS) 79
6.5.1 NGS DATA ANALYSIS SOFTWARE & WORKBENCHES 80
6.5.2 NGS DATA ANALYSIS SERVICES 81
6.5.3 NGS STORAGE, MANAGEMENT, AND CLOUD COMPUTING SOLUTIONS 82
7 NEXT-GENERATION SEQUENCING MARKET, BY TECHNOLOGY 83
7.1 INTRODUCTION 84
7.2 SEQUENCING BY SYNTHESIS 85
7.3 ION SEMICONDUCTOR SEQUENCING 87
7.4 SINGLE-MOLECULE REAL-TIME SEQUENCING 88
7.5 NANOPORE SEQUENCING 89
8 NEXT-GENERATION SEQUENCING MARKET, BY APPLICATION 90
8.1 INTRODUCTION 91
8.2 DIAGNOSTICS 92
8.3 DRUG DISCOVERY 94
8.4 BIOMARKER DISCOVERY 95
8.5 PRECISION MEDICINE 96
8.6 AGRICULTURE & ANIMAL RESEARCH 98
8.7 OTHER APPLICATIONS 99
9 NEXT-GENERATION SEQUENCING MARKET, BY END USER 101
9.1 INTRODUCTION 102
9.2 RESEARCH CENTERS AND ACADEMIC & GOVERNMENT INSTITUTES 103
9.3 HOSPITALS & CLINICS 104
9.4 PHARMACEUTICAL & BIOTECHNOLOGY COMPANIES 105
9.5 OTHER END USERS 106
10 NEXT-GENERATION SEQUENCING MARKET, BY REGION 107
10.1 INTRODUCTION 108
10.2 NORTH AMERICA 109
10.2.1 U.S. 110
10.2.1.1 Favorable government funding scenario in the U.S. market 110
10.2.1.2 Growing focus of NGS market players on strengthening their presence in the U.S. 110
10.2.1.3 Increasing number of NGS conferences in the U.S. 111
10.2.2 CANADA 111
10.2.2.1 Favorable government funding scenario in Canada 111
10.2.2.2 Growing focus of market players on expanding their presence in Canada 112
10.3 EUROPE 116
10.3.1 MARKET PLAYERS CAPITALIZING ON OPPORTUNITIES IN THE EUROPEAN NGS MARKET 117
10.3.1.1 Launch of new and advanced products and services 117
10.3.1.2 Partnerships/agreements/collaborations 117
10.3.2 GERMANY, U.K., AND BELGIUM: MAJOR HUBS FOR SCIENTIFIC RESEARCH 118
10.3.3 GROWING FUNDING AND INVESTMENTS FOR NGS IN EUROPE 118
10.4 ASIA-PACIFIC 123
10.4.1 GROWING FOCUS OF DOMESTIC AND MULTINATIONAL PLAYERS ON APAC MARKET 124
10.4.1.1 Launch of advanced NGS products and services 124
10.4.1.2 Partnerships/collaborations/agreements to co-develop advanced NGS products and services 124
10.4.2 FAVORABLE GOVERNMENT FUNDING SCENARIO 125
10.4.3 CONFERENCES/SEMINARS/TRAINING PROGRAMS 125
10.5 REST OF THE WORLD (ROW) 130
10.5.1 FOCUS OF KEY MARKET PLAYERS ON EXPANDING THEIR PRESENCE IN ROW COUNTRIES 131
10.5.2 WORKSHOPS AND CONFERENCES 131
10.5.3 FAVORABLE INITIATIVES BY PUBLIC AND PRIVATE ORGANIZATIONS 132

11 COMPETITIVE LANDSCAPE 136
11.1 OVERVIEW 136
11.2 MARKET SHARE ANALYSIS 137
11.3 COMPETITIVE SITUATION AND TRENDS 138
11.3.1 PRODUCT LAUNCHES, PRODUCT ENHANCEMENTS, AND SERVICE LAUNCHES 139
11.3.2 AGREEMENTS, PARTNERSHIPS, COLLABORATIONS, AND CONTRACTS 140
11.3.3 MERGERS AND ACQUISITIONS 141
11.3.4 EXPANSIONS 142
11.3.5 OTHER DEVELOPMENTS 142
12 COMPANY PROFILES 144
(Introduction, Products & Services, Strategy, & Analyst Insights, Developments, MnM View)*
12.1 INTRODUCTION 144
12.1.1 GEOGRAPHIC BENCHMARKING 144
12.2 ILLUMINA, INC. 145
12.3 THERMO FISHER SCIENTIFIC INC. 156
12.4 PACIFIC BIOSCIENCES OF CALIFORNIA, INC. 164
12.5 QIAGEN N.V. 169
12.6 BEIJING GENOMICS INSTITUTE 176
12.7 PERKINELMER, INC. 181
12.8 F. HOFFMANN-LA ROCHE AG 184
12.9 AGILENT TECHNOLOGIES, INC. 188
12.10 GATC BIOTECH AG 195
12.11 OXFORD NANOPORE TECHNOLOGIES, LTD. 198
12.12 MACROGEN, INC. 200
12.13 EUROFINS SCIENTIFIC 204

*Details on MarketsandMarkets view, Introduction, Product & Services, Strategy, & Analyst Insights, New Developments might not be captured in case of unlisted companies.
13 APPENDIX 206
13.1 DISCUSSION GUIDE 206
13.2 KNOWLEDGE STORE: MARKETSANDMARKETS’ SUBSCRIPTION PORTAL 210
13.3 INTRODUCING RT: REAL-TIME MARKET INTELLIGENCE 212
13.4 AVAILABLE CUSTOMIZATIONS 213
13.5 RELATED REPORTS 214
13.6 AUTHOR DETAILS 215

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