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[ 英語タイトル ] Downstream Processing Market by Technique (Separation, Concentration, Purification), Product (Chromatography Column & Resin, Filter, Single use), Application (Mab Production), End User (Contract Manufacturing Organization) - Global Forecast to 2021


Product Code : MNMHC00108080
Survey : MarketsandMarkets
Publish On : August, 2021
Category : Healthcare and Pharmaceuticals
Study Area : Global
Report format : PDF
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[Report Description]

The global downstream processing market is projected to reach USD 22.03 billion by 2021 from USD 10.32 billion in 2016, at a CAGR of 16.4% from 2016 to 2021. Increasing demand for biopharmaceuticals and increasing R&D expenditure in the biopharmaceutical industry are the major factors driving the growth of the global downstream processing market.

Developing markets in Asia-Pacific such as Japan, China, India, South Korea, Taiwan, Australia, and Singapore are lucrative markets for downstream processing, rising geriatric population, growing per capita income, increasing investments in the healthcare industry by key market players, and increasing outsourcing services by various pharmaceutical companies from these countries are the major factors driving the growth of the downstream processing market in this region.

In this report, the downstream processing market is broadly segmented on the basis of technique, product, application, end user, and region. Based on application, the downstream processing market is classified into monoclonal antibody (mAbs) production, vaccine production, insulin production, immunoglobulin production, erythropoietin production, and other applications. The mAbs production segment is expected to grow at the fastest CAGR during the forecast period. This high growth is attributed to the increasing adoption of targeted immunotherapy and increasing number of U.S. FDA-cleared therapeutic monoclonal antibodies.

On the basis of technique, the market is segmented into purification, solid-liquid separation, and clarification/concentration. In 2016, the purification segment accounted for the largest share of the downstream processing market. The large share as well as the high growth of this segment is attributed to the growing need for highly pure biopharmaceutical products.

On the basis of product, the downstream processing market is segmented into chromatography columns and resins, filters, membrane adsorbers, single-use products, and other products. In 2016, the chromatography columns and resins segment accounted for the largest share of the downstream processing market. The constant need for newer and different types of columns and resins is likely to fuel market growth.

On the basis of end user, the downstream processing market is segmented into biopharmaceutical manufacturers and contract manufacturing organizations (CMOs). The contract manufacturing organizations (CMOs) segment is expected to grow at the highest CAGR during the forecast period.
New and innovative product launches was the dominant strategy adopted by key industry participants to increase their market share and cater to unmet needs. Thermo Fisher Scientific Inc. (U.S.), GE Healthcare (U.S.), Sartorius Stedim Biotech S.A. (France), Merck Millipore (Germany), and Danaher Corporation (U.S.) are some of the leading manufacturing companies that adopted this strategy.
Research Coverage:
From an insight perspective, this research report focuses on qualitative data, market size, and growth of various segments and subsegments, competitive landscape, and company profiles. The qualitative data covers various levels of industry analysis such as market dynamics (drivers, restraints, opportunities, and challenges). The report also offers market sizes and data on the growth of various segments of the industry. It focuses on emerging and high-growth segments, and high-growth regions. The competitive landscape covers growth strategies adopted by industry players in the last three years. The company profiles comprise basic views on key players in the downstream processing market and the product portfolios, developments, and strategies adopted by market players to maintain and increase their market shares in the near future. The above-mentioned market research data, current market size, and forecast of future trends will help key players and new entrants to make the necessary decisions regarding product offerings, geographical focus, change in approach, R&D investments for innovations in products and technologies, and levels of output in order to remain successful.

Reasons to buy this report:
From an insight perspective, this research report focuses on various levels of analysis—industry analysis (industry trends) and company profiles, which together comprise and discuss the basic views on the competitive landscape; emerging and high-growth segments of the downstream processing market; high-growth regions; and market drivers, restraints, and opportunities.

The report provides insights on the following pointers:
• Market Penetration: Comprehensive information on products offered by the top players in the downstream processing market
• Product Development/Innovation: Detailed insights on the upcoming technologies, research & development activities, and new product launches in the downstream processing market
• Market Development: Comprehensive information about lucrative emerging markets—the report analyzes the markets for downstream processing products across various regions
• Market Diversification: Exhaustive information about new products, untapped geographies, and recent developments in the downstream processing market
• Competitive Assessment: In-depth assessment of market ranking, strategies, products, and manufacturing capabilities of the leading players in the downstream processing market

TABLE OF CONTENTS

1 INTRODUCTION 12
1.1 OBJECTIVES OF THE STUDY 12
1.2 MARKET DEFINITION 13
1.2.1 MARKETS COVERED 13
1.2.2 YEARS CONSIDERED FOR THE STUDY 13
1.3 CURRENCY 14
1.4 LIMITATIONS 14
1.5 STAKEHOLDERS 14
2 RESEARCH METHODOLOGY 15
2.1 MARKET SIZE ESTIMATION 16
2.2 MARKET BREAKDOWN AND DATA TRIANGULATION 19
2.2.1 KEY DATA FROM SECONDARY SOURCES 20
2.2.2 KEY DATA FROM PRIMARY SOURCES 20
2.2.2.1 Key industry insights 21
2.3 ASSUMPTIONS FOR THE STUDY 22
3 EXECUTIVE SUMMARY 23
4 PREMIUM INSIGHTS 28
4.1 DOWNSTREAM BIOPROCESSING MARKET SNAPSHOT, 2016 VS. 2021 28
4.2 DOWNSTREAM BIOPROCESSING MARKET, BY PRODUCT AND REGION 29
4.3 DOWNSTREAM BIOPROCESSING MARKET, BY TECHNIQUE,
2016 VS. 2021 (USD BILLION) 30
4.4 DOWNSTREAM BIOPROCESSING MARKET, BY APPLICATION,
2016 VS. 2021 (USD BILLION) 30
4.5 DOWNSTREAM BIOPROCESSING MARKET, BY END USER,
2016 VS. 2021 (USD BILLION) 31
4.6 DOWNSTREAM BIOPROCESSING MARKET, BY REGION 31
5 MARKET OVERVIEW 32
5.1 INTRODUCTION 33
5.1.1 DRIVERS 34
5.1.1.1 Increasing demand for biopharmaceuticals 34
5.1.1.2 Increasing R&D expenditure in biopharmaceutical companies 35
5.1.2 RESTRAINTS 35
5.1.2.1 High cost of instruments 35
5.1.3 OPPORTUNITIES 35
5.1.3.1 Patent expiry 35

5.1.4 CHALLENGES 36
5.1.4.1 Purification bottleneck 36
5.1.4.2 Lack of single-use options 36
5.1.4.3 Dearth of skilled professionals 37
6 DOWNSTREAM BIOPROCESSING MARKET, BY TECHNIQUE 38
6.1 INTRODUCTION 39
6.2 PURIFICATION TECHNIQUES 41
6.2.1 GEL CHROMATOGRAPHY 41
6.2.2 ION EXCHANGE CHROMATOGRAPHY 41
6.2.3 AFFINITY CHROMATOGRAPHY 41
6.2.4 HYDROPHOBIC INTERACTION CHROMATOGRAPHY 41
6.3 SOLID-LIQUID SEPARATION 43
6.3.1 FILTRATION 43
6.3.1.1 Tangential flow filtration 43
6.3.1.2 Normal flow filtration 43
6.3.2 CENTRIFUGATION 43
6.4 CLARIFICATION/CONCENTRATION 45
7 DOWNSTREAM BIOPROCESSING MARKET, BY PRODUCT 47
7.1 INTRODUCTION 48
7.2 CHROMATOGRAPHY COLUMNS AND RESINS 49
7.3 FILTERS 51
7.4 MEMBRANE ADSORBERS 52
7.5 SINGLE-USE PRODUCTS 53
7.6 OTHER PRODUCTS 55
8 DOWNSTREAM BIOPROCESSING MARKET, BY APPLICATION 56
8.1 INTRODUCTION 57
8.2 MONOCLONAL ANTIBODY PRODUCTION 58
8.3 VACCINES PRODUCTION 60
8.4 INSULIN PRODUCTION 62
8.5 IMMUNOGLOBULIN PRODUCTION 63
8.6 ERYTHROPOIETIN PRODUCTION 65
8.7 OTHER APPLICATIONS 66
9 DOWNSTREAM BIOPROCESSING MARKET, BY END USER 68
9.1 INTRODUCTION 69
9.2 BIOPHARMACEUTICAL MANUFACTURERS 70
9.3 CONTRACT MANUFACTURING ORGANIZATIONS 71

10 DOWNSTREAM BIOPROCESSING MARKET, BY REGION 73
10.1 INTRODUCTION 74
10.2 NORTH AMERICA 75
10.2.1 U.S. 79
10.2.2 CANADA 82
10.3 EUROPE 84
10.4 ASIA-PACIFIC 86
10.5 REST OF THE WORLD 90
11 COMPETITIVE LANDSCAPE 92
11.1 OVERVIEW 92
11.2 COMPARATIVE ASSESSMENT OF KEY MARKET PLAYERS 93
11.3 COMPETITIVE SITUATIONS AND TRENDS 93
11.3.1 PRODUCT LAUNCHES 94
11.3.2 ACQUISITIONS 95
11.3.3 EXPANSIONS 96
11.3.4 COLLABORATIONS 97
11.3.5 OTHER STRATEGIES 97
12 COMPANY PROFILES 98
(Overview, Products and Services, Financials, Strategy & Development)*
12.1 INTRODUCTION 98
12.2 THERMO FISHER SCIENTIFIC INC. 99
12.3 GE HEALTHCARE 104
12.4 SARTORIUS STEDIM BIOTECH S.A. 107
12.5 MERCK MILLIPORE 111
12.6 DANAHER CORPORATION 114
12.7 3M COMPANY 116
12.8 BOEHRINGER INGELHEIM 118
12.9 LONZA GROUP AG 120
12.10 EPPENDORF AG 122
12.11 FINESSE SOLUTIONS, INC. 124
*Details on Overview, Products and Services, Financials, Strategy & Development might not be Captured in case of Unlisted Companies.

13 APPENDIX 126
13.1 INSIGHTS OF INDUSTRY EXPERTS 126
13.2 DISCUSSION GUIDE 127
13.3 OTHER DEVELOPMENTS 130
13.4 KNOWLEDGE STORE: MARKETSANDMARKETS’ SUBSCRIPTION PORTAL 133
13.5 INTRODUCING RT: REAL-TIME MARKET INTELLIGENCE 135
13.6 AVAILABLE CUSTOMIZATIONS 137
13.7 RELATED REPORTS 138
13.8 AUTHOR DETAILS 139

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